Manufacturing capacity landscape and scaling strategies for fermentation derived protein

Fermentation – Derived Protein

Manufacturing capacity landscape and scaling strategies

Fermentation-derived products are a rapidly growing category within the alternative protein space. Driven by innovations in biotechnology – enabling microbes such as yeast and bacteria to produce proteins, fats, oils and other ingredients – many foods can now be made using animal-free methods. These advancements have set the stage for fermentation-derived products to earn a widespread presence in food formulations and on store shelves.

The biomass fermentation industry, in particular, has seen a rapid diversification in microbial species, production methods and consumer products. To ensure long-term category growth, the industry must identify and address limitations in manufacturing capacity and technical capabilities to accommodate rising demand and ever-improving innovations in microbial biotechnology and fermentation approaches.

In partnership, The Good Food Institute and Integration developed this report that supports industry decision-making. It captures the global manufacturing capacity landscape of fermentation-derived products, exploring the trade-offs of strategies to scale manufacturing capacity – from partnering with contract manufacturing organizations to constructing greenfield or brownfield sites and retrofitting used equipment.

The report combines data analysis, industry-wide insights and viewpoints from a diverse range of players across the fermentation-derived product value chain to provide an overview of challenges facing these product manufacturers along with valuable considerations for how to address them.


There is a notable lack of capacity outside of Europe and North America, particularly on a commercial scale.

The combined capacity of CMOs and in-house producers is predominately concentrated in Europe, accounting for 47 percent of total capacity, and North America, with 34 percent. Minimal capacity is registered outside of these regions, with Mexico, Singapore, and South Korea are the markets with the largest capacity outside of North America and Europe.

Even in markets at a higher level of biotechnological advancement (such as the U.S.), there is an opportunity to expand fermentation-derived product manufacturing capabilities.

There is greater demand in North America, APAC, Africa and the Middle East compared to Europe or Latin America. This relationship suggests that producers in the United States seeking to outsource production may be more inclined to choose Europe or Latin America due to available capacity.

Despite the U.S. containing a significant percentage of the global fermentation-derived product capacity (34%), there remains the opportunity to develop regional capacity for food-grade fermentation.

Solutions for the road ahead:

The fermentation industry urgently needs to increase capacity at pilot and demo scale in the short term. This means procuring and developing opportunities now to enable achieving commercial-scale operations for the industry’s long-term capacity needs.

A variety of strategies exist for companies seeking to scale up production along each step of the technology development process (R&D to pilot, pilot to demo, and demo to commercial). Our analysis focuses on two critical strategic decisions from the perspective of the producer at each step in the scale-up process:

  • either partnering with a contract manufacturing organization or building a proprietary facility
  • either building a greenfield facility or pursuing brownfield development of an existing facility when seeking the proprietary option

These decisions can be evaluated using six decision factors, which are broadly applicable to industry players but may be weighed differently depending on a company’s specific context.

For more insights into the manufacturing capacity landscape of fermentation-derived proteins, along with key considerations for businesses seeking to carve out a future in this space, download the full report.

Para receber o conteúdo completo preencha o formulário abaixo.

Talk to us

Freya Tomley

Freya Tomley is an senior manager at Integration and has been working at the London Office since 2015. Freya has a wide range of experience in implementation and project and program management across new business/product launches, M&As (post-merger integration), and efficiency-driving initiatives (e.g. internal restructuring, systems implementation, commercial planning). In the last few years, she [...]

Jamie Gale

Jamie Gale is a partner at our  London Office. He has spent more than 25 years in the consulting industry and private sector. Jamie is recognized for his extensive experience in digital, developing and executing strategies that enable business transformation. He has supported clients across manufacturing, retail, telecommunications, financial services, food & beverage and transportation [...]

Julian Lempp

Julian Lempp is a senior director at Integration's Munich Office. He has experience both within consulting and industry, having previously worked for a leading German consultancy and as a business development manager within an industrial goods manufacturer. While he has experience across many project types, his specialization lies in supply chain, having undertaken numerous consulting [...]

Rodrigo Seabra

Rodrigo Seabra is the partner at our Office in Munich. He joined Integration in 2006 in Brazil and led the Mexico Office, before taking on responsibility of the Munich Office. Rodrigo is part of our Implementation Practice, has amassed international experience in industries such as consumer goods, retail, food & beverage, pharmaceutical and healthcare and [...]

Sven Hoffmann

Sven Hoffmann is a senior manager at Integration's Munich Office. His experience covers projects in the areas of strategic planning and roadmaps, organizational and process redesigns, go-to-markets and innovation systems. Sven has worked in projects across Asia, Europe, North and South America. He holds a master's degree in technology management from the Technical University of [...]

  • On 25 July 2023